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KMID : 1101420190510010105
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Korean Journal of Clinical Laboratory Science
2019 Volume.51 No. 1 p.105 ~ p.113
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Study on Correlation between Cognitive Impairment and Geriatric Depression or Geriatric Stress
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Kim Dae-Jin
Cho Soo-Young
Choi Jeong-Su
Lee Min-Woo
Cho Eun-Kyung
Kang Se-Hee
Kim Suhng-Wook
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Abstract
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This study examined the effects of geriatric depression and geriatric stress on cognitive impairment. In particular, the dementia groups were divided into Alzheimer’s disease and vascular dementia. A normal group was used as the control group. For each group, the geriatric depression using the geriatric depression scale (GDS) and geriatric stress using the geriatric stress scale (GSS) was compared with the regression and correlation results of cognitive impairment. Statistical tests, such as descriptive statistics, Kruskall-Wallis, correlation analysis, and multiple regression analysis, were performed. For the Alzheimer’s group, the GDS and GSS correlated with the cognitive impairment, but only the GDS showed a cause-and-effect relationship with cognitive impairment. In particular, the male group with Alzheimer’s disease showed clear confirmation. In addition, geriatric stress was found to be associated with geriatric depression. In conclusion, geriatric depression affects the cognitive impairment directly and geriatric stress affects the cognitive ability indirectly through geriatric depression. In this study, the Alzheimer’s disease, vascular dementia, and control groups had a small sample size. Therefore, the external validity in future studies can be increased using a larger sample size for each group.
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KEYWORD
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Alzheimer’s disease, Cognitive impairment, Geriatric depression, Geriatric stress, Vascular dementia
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